Our latest research findings in drug discovery and ADME/Tox are illustrated through posters presented at conferences like SBS, AACR and others; and through peer-reviewed articles.  View some of our most recent scientific posters by clicking the tabs below.

Poster Title Authors
High-throughput LanthaScreen® cellular assays for interrogating post-translational modifications of p53 and histone H3Mark Federici, Thomas Machleidt, Spencer Hermanson, Coby Carlson and Kun Bi
Next-generation cell-based imaging assays for apoptosis and oxidative stress from Molecular ProbesDaniel Beacham, Michelle Yan, Scott Clarke, Bhaskar Mandavilli, Bonnie Hanson, Shih-Jung Huang, Upinder Singh, Michael Janes and Nicholas Dolman
NA-Fluor™ and NA-XTD™ influenza neuraminidase assays for neuraminidase quantitation and inhibition assaysAnthony C. Chiulli, Corinne E. Miller, Albana Mihali, Laura Thibodeau, Rouh-Rong Juo, Brian D’Eon, and Melissa A. Gee
Endogenous GPCR transcript profiling of Life Technologies primary cell offerings: Opening the door to physiologically relevant cell systems for pharmaceutical screensRhonda A. Newman & David T. Kuninger
Primary human cells from Life Technologies—offerings, scale, and applications in HCS and HTS formats
David Kuninger, Nick Dolman, Kevin Chambers, Coby Carlson and Daniel Beacham
Next-generation chemiluminescent secreted placental alkaline phosphatase (SEAP) reporter gene assayCorinne E. Miller, Laura Thibodeau, and Brian J. D’Eon
Expression, capture and display of native GPCRs on soluble mammalian membrane particlesSanjay Vasu, Wen Chen, Julia Fletcher, Kristin Huwiler, Wieslaw Kudlicki, Kevin Lowitz
The PrestoBlue™ Cell Viability Reagent: Measure cell viability in a fraction of the timeBonnie J. Hanson, Michael Hancock, Leisha Kopp, Uma Lakshmipathy
A substrate-independent histone deacetylase inhibitor assaySteve Riddle, Steve Fakhoury, Bryan Marks, Hildegard Eliason and Jack Frazee
Simply sensitive: Phosphate detection made easyKevin R. Kupcho, Caroline M. Wessely, Steve M. Riddle, and Kevin L. Vedvik
Monitoring post-translational modifications and protein-protein interactions using a proximity ligation assay
Kristin G. Huwiler, Tina Settineri, Rica Bruinsma, Bryan Marks, Mark Shannon, Dave Ruff, & Barry Schweitzer
A flexible kinase inhibitor assay platform for active, non-activated, and impure kinase preparations
Caroline Wessely, Connie Lebakken, Laurie Reichling, Jason Ellefson, Kun Bi and Steve Riddle
Poster Title Authors
Cryopreserved HepaRG™ Cells: An Alternative In Vitro Screening Tool for Human Hepatic Drug Metabolism
Julie Price, Jonathan P. Jackson, James Lovgren, Stephen S. Ferguson
Developing applications for primary astrocytes to enable drug discoveryRoland Leathers, Spencer Hermanson, Lucas Chase, Connie Lebakken, and Kun Bi
Generation of Zero-footprint iPSCs in Xeno Free or Feeder Free with CytoTune™ -iPS Reprogramming KitGillian Wallace, Chad MacArthur, Andrew Fontes, Jasmeet Kaur, Mohan Vemuri, and Pauline T. Lieu
High Quality Episomal Human iPSC derived from Cord Blood with a Zero Footprint: Applications in Serum-Free and Xeno-Free Culture Robby Kelchtermans, Shruthi Pal, Jasmeet Kaur, MacArthur Chad, Ann Peters, Tea Soon Park, Xuan Yuan, Paul Burridge, Udaykumar Kolkundkar, Elias Zambidis, Mohan Vemuri
High-Throughput LanthaScreen® Cellular Assays for Interrogating Post-Translational Modifications of p53 and Histone H3Ann MacDonald, Mark Federici, Thomas Machleidt, Spencer Hermanson, Coby Carlson and Kun Bi
Next Generation Cell Engineering: The Jump-In™ Cell Engineering PlatformRoland Leathers, Thomas Machleidt, David Thompson, Beth Frey, Leisha Kopp, Bonnie Hanson, David Piper, Justin Wetter
Monitoring Post-Translational Modifications and Protein-Protein Interactions using the Proximity Ligation AssayNicol Watson, Kristin G. Huwiler, Tina Settineri, Rica Bruinsma, Bryan Marks, Mark Shannon, Dave Ruff, and Barry Schweitzer
The Next Generation of Cell-Based Imaging Assays for Apoptosis, Autophagy and Oxidative Stress from Molecular Probes®Nicol Watson, Daniel Beacham, Michelle Yan, Scott Clarke, Bhaskar Mandavilli, Bonnie Hanson, Shih-Jung Huang, Upinder Singh, Michael Janes and Nicholas Dolman
Novel live alkaline phosphatase substrate for identification of pluripotent stem cellsJoanne Hulme, Rene H. Quintanilla, Upinder Singh, Scott Grecian, Kyle Gee, Mahendra Rao, Uma Lakshmipathy