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Life Technologies offers a collection of target-based ADME/Tox assays for drug discovery and development to help you determine the metabolic and safety profiles of lead candidates on a high throughput scale.

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Featured Target-Based ADME/Tox Assay Categories

P450 Assays

Fluorescent substrates and recombinant enzymes to evaluate your compound’s potential impact on P450 activity

  Transporter Products
GenoMembrane Transporter Vesicles and Transporter-qualified Hepatocytes to facilitate the prediction of your compounds modulation of transport enzyme activity
 
Biochemical hERG Assays
Detect hERG channel binding without radioactivity using our Predictor™ hERG Flourescence Polarization Assay Kit ideal for HTS applications

  Nuclear Receptor ADME Assays

Our LanthaScreen® PXR (SXR) and CAR Competitive Binding Assays contains all the reagents you need to conduct compound affinity testing

 
G-Protein Coupled Receptor Cellular ADME Assays

Avoid off-target effects with our GPCR toxicity panel of validated cellular assays for selectivity screening

  Toxicology Products

Assays to identify indicators of both biochemical and cellular toxicity

 
PCR-Based Drug Discovery Assays
Analyze drug discovery-related genes using our real-time PCR arrays

SelectScreen® Services

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Expect more with P450 and hERG screening services


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ADME/Tox eNews

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ADME/Tox News - insight into products, techniques, promotions and events

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ADME/Tox Resources

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Scientific references, protocols, videos, and much more


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For Research Use Only. Not for use in diagnostic procedures.

ADME/Tox Resources

For Research Use Only. Not for use in diagnostic procedures.