CRISPR design tool
GeneArt® Precision TALs

Precise, efficient gene sequence targeting and modification technologies

From precision genome editing and gene modification technologies to high-efficiency delivery systems, we have developed a broad range of solutions to help you create the modified genes, expression systems, and stable cell lines you need for your research—from culturing cells to modification, detection, and analysis. Our technologies—including GeneArt® TALs and CRISPRs—enable you to reliably modify genomic sequences and analyze the phenotypic outcomes. In addition, we can deploy a combination of advanced technologies to produce a custom construct or cell line that meets your specifications. Balancing performance and cost, our cell engineering portfolio is built on 20 years of industry-leading innovation and can grow with your research needs.

Which technology?   Request Genome Editing eBook  

Featured Technologies

Precise and flexible editing; targeting to any gene in any cell, with all-around freedom.

Perform siRNA- or miRNA-mediated loss-of-function analysis in eukaryotic systems.

Generate isogenic cell lines in your preferred cell background in much less time compared to traditional methods.

Rapid and efficient editing with multiplexing capabilities.
 

The world's largest collection of ready-to-go CRISPR engineered cell lines.

Essential tools for monitoring the efficiency of your genome editing experiments.

Featured Applications

plant-sciences

Tools for plant genome editing, cloning, DNA assembly, amplification, and analysis, plus Agrobacterium tumefaciens LBA4404 for transformation.

stem-cell-engineering

Modify and study gene and protein expression, and explore disease and differentiation pathways, using a variety of gene delivery techniques.

custom-cell-line-services

We now offer both off-the-shelf engineered cell lines and custom design and engineering services to deliver the cell lines you need with high quality and service.

Need assistance with CRISPR gRNA design?

Our new CRISPR Search & Design tool allows you to search our database of >600,000 predesigned CRISPR gRNAs in human and mouse genes or analyze your sequence of interest for de novo gRNA designs using our proprietary algorithms. Up to 25 gRNA sequences per gene are provided with recommendations based on potential off-target effects for each CRISPR sequence.

Start designing today

Technical resources

Cell engineering and genome editing webinars

Further your knowledge by registering for our latest live webinars, or view one of our recorded webinars at your leisure.

Genome editing publications

Gain insight and find in-depth technical information for your experiments with the latest genome editing publications; also see our genome editing poster series.

CRISPR-Cas9 Technology

New Genome Editing Support Center
Find tips, troubleshooting help, and resources for your genome editing applications

 

 

Downloadable tools

Web resources