Precise, efficient gene sequence targeting and modification technologies
From precision genome editing and gene modification technologies to high-efficiency delivery systems, we have developed a broad range of solutions to help you create the modified genes, expression systems, and stable cell lines you need for your research—from culturing cells to modification, detection, and analysis. Our technologies—including GeneArt® Precision TALs and CRISPRs—enable you to reliably modify genomic sequences and analyze the phenotypic outcomes. In addition, we can deploy a combination of advanced technologies to produce a custom construct or cell line that meets your specifications. Balancing performance and cost, our cell engineering portfolio is built on 20 years of industry-leading innovation and can grow with your research needs.
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Target any locus in the genome using custom DNA binding proteins for precise genome editing.
Perform siRNA- or miRNA-mediated loss-of-function analysis in eukaryotic systems.
Generate isogenic cell lines in your preferred cell background in much less time compared to traditional methods.
Edit and engineer the genomic locus of your choice from a single plasmid in a sequence-specific manner.
GeneArt® Cell Lines and Proteins are a suite of service offerings designed to help facilitate protein expression in mammalian cell lines.
Create single-copy isogenic cell lines using Flp recombinase–based vectors and parental cell lines containing stably integrated Flp recombination target (FRT) sites.
Tools for plant genome editing, cloning, DNA assembly, amplification, and analysis, plus Agrobacterium tumefaciens LBA4404 for transformation.
Modify and study gene and protein expression, and explore disease and differentiation pathways, using a variety of gene delivery techniques.
Allow us to generate high-performance cell lines with stable expression of your gene using a combination of our advanced technologies.
Further your knowledge by registering for our latest live webinars, or view one of our recorded webinars at your leisure.
Gain insight and find in-depth technical information for your experiments with the latest genome editing publications; also see our genome editing poster series.
For Research Use Only. Not for use in diagnostic procedures.