Ion AmpliSeq™ Community Panels
OncoNetwork Consortium:Get the researchers’ perspective
on community panels
Leveraging the power of the Ion Community and Ion AmpliSeq™ technology, Life Technologies delivers Ion AmpliSeq™ Community Panels. Designed with leading disease researchers, Ion AmpliSeq™ Community Panels provide the ability to selectively analyze gene content with the aim of transforming cancer and inherited disease research. Your disease research is greatly simplified with the community wide-availability of these panels. In addition, for maximum flexibility, you will be able to rapidly customize any Ion AmpliSeq™ Community Panel to advance clinical research to fit your own project requirements.
Ion AmpliSeq™ Colon and Lung Cancer Panel
- Analyzes hotspots in 22 genes with coverage of over 500 mutations implicated in colon and lung cancer. The gene content of this panel is designed with a consortium of 8 leading researchers and is currently being tested using 180 different samples including FFPE tissue.
- OncoNetwork consortium members include: Drs. Christoph Noppen1, Aldo Scarpa2, Pierre Laurent Puig3, Nicola Normanno4, Ian Cree 5, Orla Sheils6, Ludovic Lacroix7, Marjolijn Ligtenberg.8
1 VIOLLIER AG Basel, Switzerland, 2ARC-NET University of Verona Italy, 3 Université Paris Descartes, Paris, France, 4 Centro Ricerche Oncologiche Mercogliano, Italy , 5 Warwick University Medical School, United Kingdom , 6 Trinity College Dublin, Ireland, EIRE, 7 Institut Gustave Roussy (IGR) Paris, France, 8 Radboud University Nijmegen Medical Centre, The Netherlands
Ion AmpliSeq™ AML Panel
- Analyzes the coding regions of known mutations in 21 commonly mutated genes in acute myeloid leukemia (AML).
- Design is currently in progress with input from Drs. Kojo Elenitoba-Johnson and Bryan Betz from the Molecular Diagnostics Laboratory at the University of Michigan, Department of Pathology.
Ion AmpliSeq™ BRCA1&2 Panel
- Analyzes the coding regions of BRCA1 and BRCA2 genes. Mutations in tumor suppressor genes BRCA1 and BRCA2 have been implicated in hereditary breast and ovarian cancer
- Design and validation is currently in progress with input from Drs. Marjolijn Ligtenberg and Arjen Mensenkamp from Radboud University Nijmegen Medical Centre, The Netherlands, and with Drs. Jose Carlos Machado and Jose Luis Costa from The Institute of Molecular Pathology and Immunology of the University of Porto.
Ion AmpliSeq™ CFTR PanelAnalyzes all exons, intron-exon boundaries and UTRs that contain common mutations in the cystic fibrosis transmembrane regulator (CFTR) gene. Mutations of this gene are associated with cystic fibrosis.
Ion AmpliSeq™ Cardio PanelAnalyzes all exons and UTRs of 62 genes commonly implicated in cardiomyopathies, channelopathies/arrhythmias, and structural heart defects.
Ion AmpliSeq™ TP53 Panel
- Analyzes all exons and UTRs of TP53 gene. This gene encodes tumor suppressor protein p53 and is one of the most studied genes in human cancer research.
- Design is currently in progress with Dr. Anne-Lise Børresen-Dale and her lab at the Norwegian Radium Hospital, Institute for Cancer Research.
Developed with input from the community, available to the community
Ion AmpliSeq™ Community Panels, designed with input from leading researchers, are currently being verified for performance and will soon be available for any lab to order via ampliseq.com:
The content provided herein may relate to products that have not been officially released and is subject to change without notice.
For Research Use Only. Not for use in diagnostic procedures.