Kit for cell reprogramming

CytoTune®-iPS 2.0 Sendai Reprogramming Kit

Newly released, the CytoTune®-iPS 2.0 Sendai Reprogramming Kit improves upon the well referenced CytoTune®-iPS Sendai Reprogramming Kit. The CytoTune®-iPS 2.0 Kit is non-integrating and still requires only one overnight incubation compared to multiple days of transductions required for mRNA reprogramming. 

This superior CytoTune® 2.0 Sendai system provides:

  • Increased reprogramming efficiency for even more colonies
  • Lower cytotoxicity to allow for smaller starting cell populations
  • Faster clearance to get to your iPSC experiments sooner

The 2.0 Kit contains a polycistronic vector which offers an increased reprogramming efficiency, up to 1.2%. This polycistronic vector has a different backbone containing new temperature sensitivity mutations to the polymerase-related genes, and this helps to clear the virus faster after reprogramming and causes less cytotoxicity to the cells.


CytoTune®-iPS Kit
0.19% efficiency

CytoTune®-iPS 2.0 Kit
0.49% efficiency

Improved reprogramming efficiency. Alkaline Phosphatase staining of iPSCs generated from human dermal neonatal fibroblasts (BJ strain) using (A) the CytoTune®-iPS Sendai Reprogramming Kit at an MOI of 5 and (B) the CytoTune®-iPS 2.0 Sendai Reprogramming Kit at an MOI of 5:5:3 shown at 21 days post-transduction.

Read more about Enabling Successful Reprogramming of Peripheral Blood Mononuclear cells to Induced Pluripotent Stem Cells with the CytoTune®  -iPS 2.0 Sendai Reprogramming Kit

Click on the links or images below to find out how the CytoTune® kits can transform your cell reprogramming.

Reduce Hands-on Time

Generate More Colonies

Use in a Broad Range of Experiments

Learn how to achieve successful reprogramming while reducing
hands-on time

 

Discover how to
generate more iPSCs
from a single experiment

Understand how integration-free CytoTune® technology can be applied
to a broad range of experiments

Ordering Information

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For research use only. Not for human or animal therapeutic or diagnostic use.