cell-engineering-genome-editing-webinars-module

In this synthetic biology webinars module, our scientists and collaborators will cover cell engineering in particular technologies, techniques, and applications. The webinars are designed to give a basic framework for learning these technologies. Each webinar also provides background information, data analysis, and helpful tips from our experienced technical support scientists and collaborators.

Recorded Cell Engineering & Genome Editing webinars

Abstract  

CRISPR-Cas9 for large-scale cell engineering

Recent advancements in molecular and cell biology have provided researchers with simple yet powerful genome editing tools like the CRISPR/Cas9 system, making it relatively easy to target and regulate user-defined endogenous genes in a sequence-specific manner. In this webinar, you’ll discover formats and workflows for successful CRISPR/Cas9 genome editing, how to edit multiple loci or alleles simultaneously, how to use the CRISPR/Cas9 system for in vivo applications and more.

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RNAi technology reveals possible targets for treating Parkinson's disease

Gene silencing through RNA interference (RNAi) has revolutionized our ability to interrogate gene function. This webinar showcases a study to highlight considerations for running large-scale RNAi screens, ranging from the basic concepts and experimental setup to computational and experimental approaches used to overcome the prevalence of off-target effects.

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An introduction to RNA-guided genome editing with CRISPR

Genome editing technique involves the use of engineered nucleases in conjunction with endogenous repair mechanisms to insert, delete, or replace a specific DNA sequence from a desired location in the genome. Recently, the Type II CRISPR/Cas bacterial adaptive immune system from Streptococcus pyogenes has been engineered and demonstrated to function as an effective gene-editing tool in various eukaryotic genomes, including mammalian. This webinar provides an overview on CRISPR/Cas9-mediated genome editing.

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Genome editing of iPSCs from Parkinson’s disease patients using TAL technology

In this webinar we examine genetic engineering of iPSCs derived from Parkinson’s disease patient samples, which provide model systems to study disease mechanisms in cell types not previously available. Next-generation tools for stem cell engineering, GeneArt® Precision TALs, offer an extremely efficient method for targeting and regulating expression at defined sequences within the genome.

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An introduction to precise genome editing with TAL effectors

Transcription activator–like (TAL) effectors are proteins expressed by plant bacterial pathogens to evade host defense mechanisms. Due to the unique and predictable code for each DNA base within the amino acid repeat regions, TAL DNA-binding domains can be custom tailored to bind any DNA sequence of choice. Designer TAL effectors are attractive tools for genome- and cell-engineering applications. This webinar is an introduction to designer TAL effectors and their applications for targeted gene editing.

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Synthetic TAL effectors for targeted gene activation in plants

The ability to selectively activate or inhibit gene expression has value in basic plant biology and agriculture. Targeted gene activation can be achieved by specifically expressing a gene of interest in a temporally and/or spatially defined manner in transgenic plants, or by directly activating endogenous gene expression in its original genetic context. Join this webinar where Dr. Neal Stewart, professor and director at the Tennessee Plant Research Center, provides novel insights into the potential applications of synthetic TALEs for targeted gene activation of transgenes in plants.

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An introduction to plant genetic engineering

This webinar introduces the newest genome-editing technology for plants, GeneArt® Precision TALs. The scientific presentation also covers other cloning and algae engineering technologies, such as Gateway® and GeneArt® gene synthesis, to support your quest to engineer the next generation of crops.

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Check out our plant sciences webinar series, dedicated to providing tools and technologies that will lead to remarkable agricultural discoveries.

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