Reactive Oxygen Species—Table 18.1
Table 18.1 Reactive oxygen species.
|Reactive Oxygen Species||Structure||Detection Reagents|
|Hydroxyl radical *||HO•|
|Peroxyl radical, including both alkylperoxyl and hydroperoxyl radicals (wherein R = H)||ROO•|
|Peroxynitrite anion †||ONOO–|
|Singlet oxygen ‡||1O2|
|* Hydroxyl radicals can also be photosensitized by malachite green isothiocyanate (M689) or generated by a N-(1,10-phenanthrolin-5-yl)iodoacetamide (P6879) metal–ligand complex. † 3-Nitrotyrosine, a product of this potent nitrating reagent, can be detected with an anti-nitrotyrosine antibody (A21285). ‡ Singlet oxygen can also be photosensitized by hypericin (H7476), rose bengal diacetate (R14000) and merocyanine 540 (M24571).|