BioProbes 66

 

 COVER STORY:
Neurons in Living ColorBacMam 2.0 Technology and Other Imaging Tools for Live-Cell Studies
The ultimate goal of many neuroscientists extends well beyond the analysis of normal brain functioning to the dissection of the cellular changes underlying the myriad of devastating neurodegenerative disorders. As highly specialized postmitotic cells, neurons sense the environment and then either store or rapidly convey this information through electrical and chemical signals that propagate along physical pathways in the brain and peripheral body, ultimately controlling behavior. Investigating these complex and dynamic processes in living neurons requires tools that can target specific neural cell functions without disrupting normal cell activities.
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