CaptureSelect™ Biotin Anti-IgG-Fc (ms) Conjugate consists of a 13 kDa recombinant single domain antibody fragment (V_HH affinity ligand) that specifically binds to the Fc part of IgG from multiple species. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.

The CaptureSelect™ Biotin Anti-IgG-Fc (ms) Conjugate allows you to:

• Detect, quantitate, and characterize IgG antibodies from multiple species (all subclasses, IgG-specific), multi-species IgG-derived Fc fusion proteins, recombinant IgG antibodies, and total IgG in plasma and/or serum samples
• Avoid cross-binding with other isotypes, such as IgA and IgM

Applications for CaptureSelect™ Biotin Anti-IgG-Fc (ms) Conjugate include ELISA, Western blot, Gyrolab™-based immunoassays, and label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).

Animal origin statement
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (V_HH) created by a proprietary technology. The V_HH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).