Genomics and proteomics search results

Novex™ Phospho-BTK pTyr223 Antibody (Novex™)

Bruton’s tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked a-gamma-globulinaemia, and has since been shown to involved in a number of signaling pathways in hemapoietic lineage. It has recently b ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
BTK [pY223]
Gene ID
695, 12229
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Epitope Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441350G
ace7db8d6539a22986e50b6cd360182a_CmgtBuyProduct

Novex™ Phospho-BTK pTyr551 Antibody (Novex™)

Bruton’s tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked a-gamma-globulinaemia, and has since been shown to involved in a number of signaling pathways in hemapoietic lineage. It has recently b ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
BTK [pY551]
Gene ID
695, 12229
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Epitope Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441355G
94491f439e3e59a609b5f47b45329fc4_CmgtBuyProduct

BTK Recombinant Human Protein

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. ...

Specifications

Gene ID
695
Species
Human
Target Gene
Bruton agammaglobulinemia tyrosine kinase
Gene Aliases
BTK, ATK, XLA
Protein Form
Full Length
Cytoplasmic
Recombinant
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_000052
Molecular Weight
81.3 kDa
Research Category
Immunology
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Z'-LYTE™
LanthaScreen® Antibody
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
TEC Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3363
6d0600c8f17a4517bfb8010768633a13_CmgtBuyProduct

Pierce™ BTK Synthetic Peptide (Thermo Scientific™)

This peptide corresponds to 16 amino acids near the amino terminus of human BTK (NT). ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PEP0203
9bdf466e005184e00c0de9e3d590830e_CmgtBuyProduct

Pierce™ BTK Antibody (7F12H4) (Thermo Scientific™)

MA5-15337 targets BTK in IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515337
450ee18b32ead6441afffe27fbecae37_CmgtBuyProduct

Pierce™ BTK Antibody (Thermo Scientific™)

A suggested positive control is U937 cell lysate. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA520085
91f6c0643069f223f3a7bc53fb319ff0_CmgtBuyProduct

Pierce™ Btk Antibody (E.127.9) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514929
4f4afa7c2afbf75955ab5327738a0bb1_CmgtBuyProduct

Pierce™ BTK Antibody (Thermo Scientific™)

PA5-27392 targets BTK in IHC (P) and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA527392
ca67b38cc52ddafe555eb99a0cb79c88_CmgtBuyProduct

Pierce™ BTK Antibody (Thermo Scientific™)

BTK plays a crucial role in B-cell ontogeny. This protein transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Defects in BTK are the cause of X-linked agammaglobulinemia type 1 (XLA). XLA is a humoral immunodeficiency disease which ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA514770
95aa5599c0bafb4dd9c9ca9045df02b1_CmgtBuyProduct

Pierce™ Phospho-BTK pSer180 Antibody (3i5) (Thermo Scientific™)

MA1-91571 detects BTK from human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
1cd4e80ad0aa4384b967436a30cb90fa_CmgtBuyProduct

TXK Recombinant Human Protein

TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors. ...

Specifications

Form
Frozen
Gene ID
TXK
Species
Human
Target Gene
TXK
Gene Aliases
TXK
Protein Form
Full Length
Cytoplasmic
Recombinant
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_003319.2
Molecular Weight
58.5 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen®
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 260-527
Protein Tag or Fusion
GST Tag
Tag Position
N-Terminal
Expression
Baculovirus
Kinase Family
TEC Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5860
c405fdcace010d6e6c30fcec44ea4f57_CmgtBuyProduct

CellSensor® NFAT-bla RA-1 Cell Line

B cell receptor (BCR)-mediated signaling pathways are important for B cell proliferation and differentiation. Abnormal B cell signaling has been linked to various diseases such as lupus, lymphoma, and various immune disorders. Antigen binding to the BCR promotes the activation of ...

Specifications

System
CellSensor™
Cell Line
RA-1
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1490
ce7892e1ec9bae1cd096101c54ec7776_CmgtBuyProduct

Pierce™ SH3BP5 Antibody (Thermo Scientific™)

PA5-30315 targets SH3BP5 in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA530315
67ee57c9be1892853b3d420696813d0a_CmgtBuyProduct

Pierce™ TFII-I Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517642
7853d7d1c55f3d3bae5524939984f55c_CmgtBuyProduct

Pierce™ SH3BP5 Antibody (Thermo Scientific™)

PA5-29416 targets SH3BP5 in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529416
1c1b4b27da8ea56fe36970ea2351d668_CmgtBuyProduct