MAPK1 (ERK2) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR5257A 100 µg 1250.00

Description

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
5e47a5d771d989d236e48f75f485ef00_CmgtBuyProduct

LanthaScreen® ERK2 U2OS Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1587 1 vial 9880.00

Description

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors   View full product details >

General Specifications

System
LanthaScreen®
Reporter
GFP (EmGFP)
Cell Line
U2OS
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
U0126
Gene Symbol
ERK2
Product Size
1 vial
Primary Agonist
EGF
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Optimal Response
EGF (EC50 = 0.83 ng/ml)
Alternate Agonists
Orthovanadate
PDGF
HGF
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1587
01e4b1cdd67c29f4deb250e1570b7dd1_CmgtBuyProduct

MAPK1 (ERK2) Recombinant Human Protein, Inactive

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3314 100 µg 416.00

Description

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.   View full product details >

General Specifications

Gene ID
5594
Species
Human
Target Gene
mitogen-activated protein kinase 1
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinases
Protein Form
Inactive
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3314
ccba60a505e3ce5a5b692521fde8b224_CmgtBuyProduct

LanthaScreen® Tb-anti-ERK2 [pThr185⁄pTyr187] Antibody

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV5209 25 µg 2800.52

Description

A part of the MAPK Pathway, ERK2 is phosphorylated at Thr185 and Tyr187 by the mitogen-activated protein kinase kinases 2 (MAP2K2) .
For use in combination with the   View full product details >

General Specifications

Readout
End Point
Reactivity
Human
Target Gene
Ser/Thr Kinases, Tyrosine Kinases
Label or Dye
Tb (Terbium)
Product Size
25 µg
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
PV5209
837a68b76082837bf35a8711c6220479_CmgtBuyProduct

LanthaScreen® Tb-anti-ERK2 [pThr185⁄pTyr187] Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV5270 1 mg 14610.00

Description

To facilitate in-house kinase assay configuration and screening, we have developed a selection of Tb-labeled phospho-specific antibodies, which may be accessed in small scale and   View full product details >

General Specifications

Form
Liquid
Host
Rabbit
Platform
Microplate Reader
Clonality
Monoclonal
Reactivity
Human
Label or Dye
Tb (Terbium)
Product Size
1 mg
Purification
Purified
Concentration
0.5 mg⁄ml
Antibody Fragment
Whole Antibody
SubClass (Isotype)
IgG
High Throughput Compatibility
High Throughput-Compatible
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
PV5270
b37135ccaf838c8c68f8bef0431ce486_CmgtBuyProduct

BacMam ERK2 [pThr185/pTyr187] Cellular Assay Kit

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
A12888 1 kit 1647.24

Description

The BacMam ERK2 [pThr185⁄pTyr187] Cellular Assay Kit is a high-throughput screening (HTS) compatible cellular immunoassay for the measuring of phosphorylation of GFP-ERK2.   View full product details >

General Specifications

System
LanthaScreen®
Readout
End Point
Technique
TR-FRET
Cell State
Cells Not Included
Gene Symbol
ERK2
Product Size
1 kit
Delivery Method
Baculovirus (BacMam System)
Detection Method
Fluorescent
Druggable Target
GPCRs
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
A12888
4709aec82fa07caa3ee5bf05c979192d_CmgtBuyProduct

LanthaScreen® ERK2 A375 Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1798 1 vial 9880.00

Description

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors   View full product details >

General Specifications

System
LanthaScreen®
Readout
End Point
Cell Line
A375
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
Raf Inhibitor I
Gene Symbol
ERK2
Product Size
1 vial
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1798
779ab5a0fd842eb63dcf966673549a89_CmgtBuyProduct

ERK1/2 [pTpY185/187] Polyclonal Antibody, Rabbit View 5 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44680G 10 blots 299.00

Description

This purified Rabbit Anti-ERK 1/2 [pTpY185/187] Polyclonal Antibody is specific to human, mouse, and rat ERK 1/2 [pT185/pY187]. Anti-ERK1/2 [pT185/pY187] antibody recognizes the   View full product details >

General Specifications

Reactivity
Human
Mouse
C. elegans
Chicken
Bovine
Rat
Xenopus
Drosophila
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 [pTpY185/187]
Gene ID
5595
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44680G
79a10412807dc5fd8bdc1cdfa49f0591_CmgtBuyProduct

ERK1/2 [pTpY185/187] Rabbit Polyclonal Antibody, Alexa Fluor® 488 Conjugate

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44680A1 100 µL 299.00

Description

ERK1/2 [pT185/PY187] ALEXA CONJ; Alexa Fluor 488 conjugated Polyclonal antibody specific to Human, Mouse, Rat ERK1+2 [pT185/pY187]. This antibody is validated for use in   View full product details >

General Specifications

Reactivity
Rat
Mouse
Human
Validated Application
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 [pTpY185/187]
Gene ID
5595
Label or Dye
Alexa Fluor® 488
Excitation⁄Emission (nm)
488⁄519
Target Modification State
Phospho
Product Size
100 µL
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
44680A1
509266fd9cc49413e008aee4c5863bc4_CmgtBuyProduct

ERK 1/2 (total) Singleplex Bead Kit View 1 Citations

See all Singleplex Assays

Catalog # Unit Size List Price
LHO0231 100 assays 299.00

Description

This Singleplex bead kit comprises the analyte specific components for the measurement of total ERK1⁄2 (Extracellular signal-Regulated protein Kinase) in cell lysates or   View full product details >

General Specifications

Marker
ERK1⁄2 (total)
System
Luminex®
Gene ID
5595
Species
Human
Platform
Luminex®
Bead Type
Polystyrene
Bead Region
57
Gene Symbol
MAPK3
Sensitivity
0.05 ng/ml
Target Gene
mitogen-activated protein kinase 3
Gene Aliases
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, MGC20180, PRKM3, p44-ERK1, p44-MAPK
Label or Dye
R-PE
Product Size
100 assays
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002737.2
NM_001109891.1
NP_001103361.1
NM_002746.2
NM_001040056.1
NP_001035145.1
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
LHO0231
e7d16f06502ec8ed8a4f4709323bac33_CmgtBuyProduct

ERK1/2 (MAP kinase) Monoclonal Antibody, Mouse (ERK-7D8) View 8 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
136200 200 µg 279.00

Description

Mouse anti-MAP Kinase (ERK1+ERK2) Monoclonal Antibody is specific to Canine, Human, Mouse, Rat, and recombinant ERK1+2. This unconjugated Mouse anti-MAP Kinase monoclonal antibody   View full product details >

General Specifications

Reactivity
Mouse
Human
Canine
Rat
Validated Application
Immunohistochemistry
ELISA
Western Blot
Electrophoretic Mobility Shift Assay
Immunoprecipitation
Host
Mouse
Clonality
Monoclonal
Clone ID
ERK-7D8
Target Gene
ERK1/2 (MAP kinase)
Gene ID
116590
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
200 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research
136200
661b745edc831396b6bee175ca07beed_CmgtBuyProduct

ERK1+2 [pT202/pY204] Rabbit Polyclonal Antibody View 4 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
368800 100 µL 299.00

Description

This rabbit anti-ERK1+2 [pT202/pY204] polyclonal antibody is specific to human and rat ERK1+2 [pT202/pY204]. ERK1+2 [pT202/pY204] polyclonal antibody recognizes the expressed   View full product details >

General Specifications

Reactivity
Human
Rat
Validated Application
Immunohistochemistry
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 (pT202/pY204)
Gene ID
5594
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Product Size
100 µL
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
368800
ecdd729df7b63751fdb2c9fa62d7fa6e_CmgtBuyProduct

ERK1/2 (pan) Polyclonal Antibody, Rabbit View 4 Citations

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Catalog # Unit Size List Price
44654G 100 µL 299.00

Description

This purified rabbit anti-ERK1/2 polyclonal antibody is specific to human, mouse, rat and bovine ERK 1+2. Anti-ERK1+2 polyclonal antibody recognizes the expressed product of the   View full product details >

General Specifications

Reactivity
Human
Mouse
Bovine
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 (pan)
Gene ID
5595
Label or Dye
Unconjugated
Product Size
100 µL
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44654G
ac53e5ebfa7e2096404b4ac75028c4ea_CmgtBuyProduct

p44/42 MAPK (ERK1/2) (pT202/pY204), Oligoclonal Antibody, ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
710318 100 µg 285.00

Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes human p44/42 MAPK (ERK1/2) [pT202/pY204].

Antibody Specifications:

• Validated   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Immunocytochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
6HCLC
Antibody Fragment
Whole Antibody
Target Gene
MAPK (ERK1/2) p44/42 (pT202/pY204)
Gene ID
5595
Gene Symbol
MAPK3
Accession Number
P27361
Gene Aliases
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Label or Dye
Unconjugated
Target Modification State
Phospho
Form
Liquid
Product Size
100 µg
Buffer
Phosphate buffered saline (PBS) with 0.09% sodium azide
Other Additives
Sodium Azide Preservative
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
710318
96912635c4e9c6f1bac1fb8bbc7df941_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 3 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3176 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine MBP Thr-97 derived   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
BBRC vol. 61, pp 559-563 (1974), JBC, vol 252, p 4888 (1978)
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAPK1, MAPK3, MAPK12, MAPK13, MAP2K1, MAP2K2, MAP3K6, MAP2K8
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
Bovine MBP, Thr-97 derived peptide S5
Consensus seq Pro-X-(Ser⁄Thr)-Pro (APRTPGGRR)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3176
80cb8917b9a3c1ff43875579b27ff363_CmgtBuyProduct