Genomics and proteomics search results

Novex™ Phospho-IR / IGF1R pTyr1162 / pTyr1163 Antibody (Novex™)

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intrac ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpY1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44804G
1c2e67c80ffd121bbbc78da53d55c7ef_CmgtBuyProduct

IGF1R Recombinant Human Protein (without Catalytic Activity Domain), His Tag

Insulin-like growth factor 1 receptor (IGF1R), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an imm ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3480
Species
Human
Expression
Mammalian
Gene Symbol
IGF1R
Gene Aliases
CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216
Protein Form
Truncated
Recombinant
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Growth Factor Receptors
Molecular Weight
150 kDa
Research Category
Immunology
Oncology
Stem Cell Research
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

10164H08H50
25dce30fc30536fff4e1a012930aecb7_CmgtBuyProduct

Novex™ Phospho-IR / IGF1R pTyr1158 Antibody (Novex™)

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intrac ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pY1158]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44802G
987ead46218d90f38486d8c1de98f145_CmgtBuyProduct

Pierce™ IGF1R Antibody (23HCLC), Abfinity™ Rabbit Oligoclonal (Novex™)

This antibody is predicted to react with mouse based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
23HCLC
Antibody Fragment
Whole Antibody
Target Gene
Insulin-like growth factor I receptor
Gene ID
3480
Gene Symbol
IGF1R
Accession Number
P08069
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Growth Factors & Receptors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710065
8ff434428485a7a6860803ba7417de1c_CmgtBuyProduct

Pierce™ Phospho-IGF1R pTyr1165 + pTyr1166 Antibody (Thermo Scientific™)

This antibody reacts with the beta chain of IGF1R. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535452
465288af505f3f2a7a6d0c171f2fb2a9_CmgtBuyProduct

Pierce™ Phospho-IGF1R pTyr1161 Antibody (Thermo Scientific™)

Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation a ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535769
57af0554afe2bfea22d33df5ba8abdd2_CmgtBuyProduct

IGF1R Recombinant Human Protein

IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers. ...

Specifications

Gene ID
3480
Species
Human
Target Gene
insulin-like growth factor 1 receptor
Gene Aliases
IGF-1R
Kinase Group
Tyrosine Kinases
Tag Position
C-Terminal
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000866
Molecular Weight
48.9 kDa
Research Category
Signal Transduction
Oncology
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Protein Tag or Fusion
His Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 960-1397
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3250
361c6af5d8880536af3e98f19922b765_CmgtBuyProduct

TaqMan® Array Human IGF1R Signaling (Applied Biosystems™)

These 96-well plates are pre-configured with the most appropriate TaqMan® Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of a ...

Specifications

Form
Dried Down
Format
96-well plate
Species
Human
Label or Dye
FAM™
Reaction Speed
Standard
Research Category
Apoptosis
Development
Biomarker-Related Pathway(s)
Neurobiology
Internal Probe Modification
MGB (Minor Groove Binder) (3')
FAM (5')
Non-Fluorescent Quencher (3')
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

4414141
12188c147eb5c1a4f62c015b4b923ad6_CmgtBuyProduct

Novex™ Phospho-IR / IGF1R pTyr1158 / pTyr1162 / pTyr1163 Antibody (Novex™)

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intrac ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpYpY1158/1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44806G
d33f97f5ec8d41b1764807cd8416b8e2_CmgtBuyProduct

AKT Pathway [phospho] Multispecies 7-Plex Panel for Luminex® Platform (Novex™)

The AKT Pathway Phospho 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and tissue h ...

Specifications

Marker
GSK-3β [pS9]
IRS-1 [pS312]
IGF-1R [pYpY1135⁄1136]
PRAS40 [pT246]
p70S6K [pTpS421⁄ 424]
IR [pYpY1162⁄1163]
Akt [pS473]
System
Luminex®
Gene ID
67605 24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508
Species
Mouse
Rat
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
AKT1
Insr
Gsk3b
Rps6kb1
Akt1s1
Akt1
RPS6KB1
INSR
IGF1R
IRS1
Igf1r
Irs1
AKT1S1
GSK3B
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001
0829ddbe39a9d92230e2b36eca12c3f7_CmgtBuyProduct

AKT Pathway (total) Multispecies 7-Plex Panel for Luminex® Platform (Novex™)

The AKT Pathway Total 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-reactive. Th ...

Specifications

Marker
IRS-1
IR
PRAS40
p70S6K
Akt
GSK-3β
IGF-1R
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337
16367, 72508, 67605, 24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Mouse
Rat
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
AKT1
Irs1
Insr
Gsk3b
Rps6kb1
Akt1s1
Akt1
RPS6KB1
INSR
IGF1R
Igf1r
AKT1S1
IRS1
GSK3B
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002
dd03a2e25a7ef4f0eb3a164912cab955_CmgtBuyProduct

IGF-1R [pY1135/pY1136] Human Kit for Luminex® Platform (Novex™)

This Singleplex bead kit comprises the analyte specific components for the measurement of IGF-1R (Insulin-like Growth Factor 1 Receptor) when phosphorylated at tyrosine 1135 and tyrosine 1136 in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed wit ...

Specifications

Marker
IGF-1R [pYpY1135⁄1136]
System
Luminex®
Gene ID
3480, 16001, 25718
Species
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
73
Gene Symbol
IGF1R
Igf1r
Sensitivity
1.3 U/ml
Target Gene
insulin-like growth factor 1 receptor
insulin-like growth factor I receptor
Gene Aliases
A330103N21Rik, CD221, D930020L01, IGF-1R, hyft
IGFIRC, JTK13, CD221, IGFIR, IGFR, JTK13, MGC142170, MGC142172, MGC18216
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_010513.2
NP_000866.1
NM_152452.1
NM_000875.3
NP_434694.1
NP_034643.2
NM_052807.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0501
ddfdba14528d7ff79a02f7cee88eec43_CmgtBuyProduct

IGF-1R [pY1135/pY1136] Phospho-ELISA Kit, Human (Novex™)

The IGF-1R [pYpY1135/1136] Human ELISA kit is designed to detect and quantify the level of IGF-1R protein phosphorylated at tyrosine residues 1135 and 1136. This assay is intended for the detection of IGF-1R [pYpY1135/1136] from human, rat and mouse cell extracts using 96-well pl ...

Specifications

Marker
IGF-1R
Gene ID
3480
Species
Mouse
Human
Rat
Platform
Microplate Reader
Gene Symbol
IGF1R
Sensitivity
<1 U⁄mL
Target Gene
insulin-like growth factor 1 receptor
Gene Aliases
CD221, IGFIR, IGFR, JTK13, MGC142170, MGC142172, MGC18216
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_152452.1
NP_000866.1
NM_000875.3
Cross-Reactivity
Mouse
Rat
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO0501
79bbe1302ac648133bb95c963da594e5_CmgtBuyProduct

AKT Pathway [phospho] Multispecies Magnetic 7-Plex Panel for Luminex® Platform (Novex™)

The AKT Pathway Phospho 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and ...

Specifications

Marker
GSK-3β [pS9]
IRS-1 [pS312]
IR [pYpY1162⁄1163]
IGF-1R [pYpY1135⁄1136]
p70S6K [pTpS421⁄ 424]
Akt [pS473]
PRAS40 [pT246]
Gene ID
24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
Species
Mouse
Rat
Human
Platform
Luminex® Instruments
FlexMAP® 3D™ System
MAGPIX® System
Luminex® 200™ System
Bead Type
Magnetic
Gene Symbol
AKT1
AKT1S1
GSK3B
IGF1R
Igf1r
Irs1
Insr
Gsk3b
Rps6kb1
Akt1s1
Akt1
RPS6KB1
INSR
IRS1
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Cell Lysates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001M
1d87bd1697571ec61fa24a87797e8098_CmgtBuyProduct

IGF-1R (total) Multispecies Kit for Luminex® Platform (Novex™)

This Singleplex bead kit comprises the analyte specific components for the measurement of total IGF-1R (Insulin-like Growth Factor 1 Receptor) in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific and total protein single ...

Specifications

Marker
IGF-1R (total)
System
Luminex®
Gene ID
3480, 16001, 25718
Species
Mouse
Rat
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
73
Gene Symbol
IGF1R
Igf1r
Sensitivity
0.042 ng/ml
Target Gene
insulin-like growth factor 1 receptor
insulin-like growth factor I receptor
Gene Aliases
MGC18216, A330103N21Rik, CD221, D930020L01, IGF-1R, hyft
IGFIRC, JTK13, CD221, IGFIR, IGFR, JTK13, MGC142170, MGC142172
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_010513.2
NP_000866.1
NM_152452.1
NM_000875.3
NP_434694.1
NP_034643.2
NM_052807.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0491
c8ab96398b4df524a5395db36cd7be05_CmgtBuyProduct