Genomics and proteomics search results

LanthaScreen® Tb-IKBa pSer32 Antibody Kit

An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB. ...

Specifications

Format
384-well plate
Gene ID
1147, 2869, 3551
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Tb (Terbium)
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3562
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Fluorescein-IKK Substrate

A fluorescein-labeled peptide substrate that is primarily used with the IkappaB kinase (IKK) family. ...

Specifications

Gene ID
1147, 2869, 3551
Substrate
Fluorescein-IKK
Label or Dye
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1864 Da
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Amino Acid Sequence
Fluorescein- DRHDSGLDSMKDE
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3507
fddf09ebd38ce054dbf1c168496d039c_CmgtBuyProduct

CHUK (IKK α) Recombinant Human Protein

CHUK (IKK alpha) is a serine⁄threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. ...

Specifications

Gene ID
114294, 1147
Species
Human
Target Gene
conserved helix-loop-helix ubiquitous kinase
Gene Aliases
CHUK (IKK α)
Kinase Group
Ser⁄Thr Kinases: Other
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_001269
Molecular Weight
88.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Adapta™
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4310
dd758bc566ac2979412021ae3590b31a_CmgtBuyProduct

CellSensor® NFkB-bla ME-180 Cell Line

The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells. The cell line was created through fluorescence activated cell sorting (FACS) of cells respons ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Cytokines
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1667
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IKK-alpha [pSpS176/180] Polyclonal Antibody, Rabbit (Novex®)

This rabbit anti-IKK-alpha [pSpS176/180] polyclonal antibody is specific to human IKK-alpha [pSpS176/180] and expected to react with mouse (not tested). IKK-alpha [pSpS176/180] polyclonal antibody recognizes the expressed product of the CHUK gene. IκB Kinase-α (IKKα) is an 85 kDa ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IKKalpha [pSpS176/180]
Gene ID
1147
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44714
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Adapta™ Universal Kinase Assay Kit

The Adapta™ Universal Kinase Assay Kit is a homogenous, fluorescence-based immunoassay for the detection of ADP produced by kinases or other ATP dependent enzymes. ...

Specifications

Format
384-well plate
Gene ID
1022, 1147, 120892, 1612, 3376, 5289, 5290, 5294, 8536
Readout
End Point
Technique
TR-FRET
Assay Type
Universal Kinase Assay
Label or Dye
Alexa Fluor® 647
Europium
Target Enzyme
Kinases (Multiple)
Validated Kinases
CAMK1, CDK7, CDK9, CHUK, LRRK2, PI4KB, PIK3C2B, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3C2A
Excitation⁄Emission (nm)
340⁄615, 665
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5099
ecac9e93265afd21eaa6cea40b5c6120_CmgtBuyProduct

IKK alpha Antibody (Thermo Scientific™)

In Western blot applications, this antibody detects a band at ~85kDa. A suggested positive control is Hela cell lysate. PA5-19897 can be used with blocking peptide PEP-0023. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519897
4e869691666a7470a8442551b6093118_CmgtBuyProduct

IKK alpha Antibody (Thermo Scientific™)

In Western blot applications, this antibody detects a band at ~85kDa. A suggested positive control is Hela cell lysate. PA5-19914 can be used with blocking peptide PEP-0040. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519914
0ca12284e596406dc5a3f30eb44281ce_CmgtBuyProduct

IKK alpha Antibody (Thermo Scientific™)

In Western blot applications, this antibody detects a band at ~85kDa. A suggested positive control is Jurkat cell lysate. PA5-19915 can be used with blocking peptide PEP-0041. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519915
d5802c2560a658d4215a1ea9a531c795_CmgtBuyProduct

CHUK Antibody (7C10B6, 1A10A10) (Thermo Scientific™)

MA5-15427 targets CHUK in WB applications and shows reactivity with Human samples. The MA5-15427 immunogen is purified recombinant fragment of CHUK (aa500-590) expressed in E. Coli. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515427
74999297d98a611768ce12fc3b999dde_CmgtBuyProduct

IKK alpha Antibody (14A231) (Thermo Scientific™)

Suggested positive control: Daudi, NIH-3T3, or Raw. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA516157
cc6082083bd8133e7c929c347abbaf1c_CmgtBuyProduct

CHUK Antibody (3G12) (Thermo Scientific™)

MA5-15691 targets CHUK in WB applications and shows reactivity with Human samples. The MA5-15691 immunogen is purified recombinant fragment of human CHUK expressed in E. Coli. MA5-15691 detects CHUK which has a predicted molecular weight of approximately 85kDa. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515691
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CHUK Antibody (3G12H9) (Thermo Scientific™)

MA5-15696 targets CHUK in FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15696 immunogen is purified recombinant fragment of human CHUK expressed in E. Coli. MA5-15696 detects CHUK which has a predicted molecular weight of approximately 85kDa ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515696
89a6879ce81aa60d1b6b45f87af7b1ab_CmgtBuyProduct

Phospho-IKK pSer176 + pSer180 Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517593
5b1efe17bb9123cc14bdc557911a1e64_CmgtBuyProduct

Phospho-IKK-alpha pSer176 + IKK-beta pSer177 Antibody (J.10.3) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514857
500c467311442ebc333f38ce5c0bf14f_CmgtBuyProduct