Genomics and proteomics search results

Novex™ Phospho-JAK2 pTyr1007 / pTyr1008 Antibody (Novex™)

Janus Activating Kinase 2 (JAK2) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine re ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44426G
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Novex™ JAK2 Antibody (691R5) (Novex™)

Janus Activating Kinase 2 (JAK2) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine re ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
691R5
Target Gene
JAK2
Gene ID
16452, 24514, 3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1352
6e1a421bbb44214d253af264e6b257b9_CmgtBuyProduct

Novex™ JAK2 Antibody (Novex™)

Janus Activating Kinase 2 (JAK2) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine re ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2
Gene ID
3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44406G
d62f7f973d5c1d43adc48f04059259c6_CmgtBuyProduct

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera. ...

Specifications

Gene ID
3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2 V617F
Protein Form
Catalytic
Recombinant
Cytoplasmic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.9 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132; V617F
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4336
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JAK2 Recombinant Human Protein

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2. ...

Specifications

Gene ID
3439, 3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2
Protein Form
Catalytic
Cytoplasmic
Recombinant
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
66.6 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 809-1153 +9
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4210
5318ff38ff5ff2e77474b25710ab2041_CmgtBuyProduct

JAK2 Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. ...

Specifications

Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2
Protein Form
Catalytic
Recombinant
Cytoplasmic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.8 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4393
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JAK2 (total) ELISA Kit, Human (Novex™)

The JAK2 (Total) ELISA kit is designed to detect and quantify the level of JAK2 protein. This assay is intended for the detection of JAK2 from human cell lysates using 96-well plates and a microplate reader. ...

Specifications

Marker
JAK2
Gene ID
3717, 16452
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Jak2
Sensitivity
<0.95 ng⁄ml
Target Gene
JAK2
Gene Aliases
AI504024, C81284, Fd17, JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
0.95-60 ng⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_004972.3
NP_032439.2
NP_004963.1
NM_008413.2
NP_001041642.1
NM_001048177.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5521
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JAK2 [pY1007/pY1008] Phospho-ELISA Kit, Human (Novex™)

The JAK2 [pYpY1007/1008] ELISA kit is designed to detect and quantify the level of JAK2 protein phosphorylated at dual tyrosine residues 1007 and 1008. This assay is intended for the detection of JAK2 [pYpY1007/1008] from human cell extracts using 96-well plates and a microplate ...

Specifications

Marker
JAK2
Gene ID
3717
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Sensitivity
1.5 U⁄ml
Target Gene
JAK2
Gene Aliases
JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_004972.3
NP_004963.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5621
a9fd7640693f3985402c2b0c32c414c7_CmgtBuyProduct

Pierce™ JAK2 Antibody (1C1) (Thermo Scientific™)

MA5-15632 targets JAK2 in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515632
2bcf00438ada037184807508bf5a7045_CmgtBuyProduct

Novex™ Phospho-Jak2 pTyr221 Antibody

Janus Activating Kinase 2 (JAK2) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine re ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A14017
03dd9d02ba7395be27bf6a87e52fabbe_CmgtBuyProduct

LanthaScreen® STAT5 (JAK2 V617F) U2OS Cell Line

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The JAK2⁄STAT5 signaling pathway plays an essential role in blood cell formation in response to cytokines such as GM-CSF, IL-3, an ...

Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
U2OS
Cell State
Dividing Cells
Antagonists
JAK Inhibitor
Gene Symbol
STAT5A
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Optimal Response
Constitutively Active
Alternate Agonists
Constitutive
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1588
2f157489fcfbc990aa3c5020f3f69a26_CmgtBuyProduct

Pierce™ Phospho-JAK2 pTyr931 Antibody (Thermo Scientific™)

Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its a ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535831
a836fc502e37653812224fed04cd468e_CmgtBuyProduct

Pierce™ Phospho-JAK2 pTyr221 Antibody (Thermo Scientific™)

Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its a ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535832
976f8a93921088e63ddd650b4408dff2_CmgtBuyProduct

Pierce™ Phospho-JAK2 pTyr570 Antibody (Thermo Scientific™)

Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its a ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535830
4caac2c03da7517b7f68ceef5fe15750_CmgtBuyProduct