JAK3 Recombinant Human Protein

See all Cytoplasmic Tyrosine Kinases

Catalog # Unit Size List Price
PV3855 10 µg 379.00

Description

Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and   View full product details >

General Specifications

Gene ID
3718
Species
Human
Target Gene
Janus kinase 3
Gene Aliases
JAK3, LJAK, JAKL
Product Size
10 µg
Protein Form
Cytoplasmic
Recombinant
Catalytic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_000206
Molecular Weight
67.4 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
Omnia® Bulk Substrate
LanthaScreen® Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 781-1124
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3855
7c815b70abf03f86e917c090bade29d0_CmgtBuyProduct

JAK3 Mouse Monoclonal Antibody (clone 515R6)

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
AHO1572 100 µg 299.00

Description

JAK3 known as Janus kinase 3 is a tyrosine kinase that belongs to the Janus family. JAK3 functions in signal transduction and interacts with members of the STAT (signal   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
515R6
Target Gene
JAK3
Gene ID
3718
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
100 µg
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
AHO1572
6cac7a3b2e2d79dcd2847a01bee34e1b_CmgtBuyProduct

Jak3 (pY980/pY981) Monoclonal Antibody (clone D44E3), Rabbit

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
A16677 100 µL 335.00

Description

This is a purified Rabbit anti-Jak3 (pY980/pY981) antibody that can be used in the validated applications of western blot.

Antibody characteristics   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D44E3
Antibody Fragment
Whole Antibody
Target Gene
tyrosine-protein kinase JAK3
Gene ID
3718
Gene Symbol
JAK3
Accession Number
P52333
Gene Aliases
JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Label or Dye
Unlabeled
Target Modification State
Phospho
Form
Liquid
Product Size
100 µL
Protein Family
Tyrosine Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Immunology & Inflammation
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
A16677
fc0a5e934d877dd6a797142cc23d687e_CmgtBuyProduct

LanthaScreen® Tb-PY20 Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3552 25 µg 906.00

Description

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.

For use in   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3552
74a2597eb8313d2f2861ebaf055d5433_CmgtBuyProduct

JAK/STAT Rabbit Polyclonal Antibody

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44429G 7 vials 415.00

Description

The purified, unconjugated antibodies in rabbit anti-JAK/STAT antibody Sample Pack are specific to human, mouse, rat, swine and monkey JAK/STAT. STATs (signal transducers and   View full product details >

General Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Clone ID
Sampler Pack
Target Gene
JAK/STAT
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
7 vials
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44429G
5ffc875262eb13026a8cb4e82941e629_CmgtBuyProduct

JAK2 [pYpY1007/1008] Polyclonal Antibody, Rabbit View 9 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44426G 10 blots 299.00

Description

This rabbit anti-JAK2 [pYpY1007/1008] polyclonal antibody is specific to mouse JAK2 [pY1007/pY1008]. JAK2 [pYpY1007/1008] polyclonal antibody recognizes the expressed product of   View full product details >

General Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44426G
49656d274f5d2650e75c16eda7b71b5f_CmgtBuyProduct

LanthaScreen® Tb-anti-pSTAT1 [pTyr701] Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4844 25 µg 2845.00

Description

A part of the JAK/STAT Pathway, STAT1 (Signal Transducer and Activator of Transcription 1) is phosphorylated at Tyr701 by the Janus family of tyrosine kinases.

For use in   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Tyrosine Kinases
Validated Kinases
JAK1, JAK2, JAK3, TYK2
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4844
2a334e63a4ff9ead83fb18b5248485a5_CmgtBuyProduct

LanthaScreen® Tb-pSTAT3 [pTyr705] Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4846 25 µg 2845.00

Description

A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.

For use in   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Tyrosine Kinases
Validated Kinases
JAK1, JAK2, JAK3, TYK2
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4846
74be8d39f8505a11268dcd3d7f307770_CmgtBuyProduct

Fluorescein-Poly GAT

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3611 1 mL 668.00

Description

A general fluorescein peptide substrate consisting of a polymer of glutamate, alanine, and tyrosine that is used to monitor tyrosine kinase activity.

For use in combination   View full product details >

General Specifications

Substrate
Fluorescein-Poly GAT
Label or Dye
FITC (Fluorescein)
Product Size
1 mL
Target Enzyme
Tyrosine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Amino Acid Sequence
Fluorescein- Poly Glu:Ala:Tyr (6:3:1)
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3611
2f7ff130727e71fa4314b503cfd9db47_CmgtBuyProduct