MAP3K8 (COT) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4313 10 µg 379.00

Description

MAP3K8 (COT) is a serine⁄threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle.   View full product details >

General Specifications

Gene ID
1326, 3459
Species
Human
Target Gene
mitogen-activated protein kinase kinase kinase 8
Gene Aliases
MAP3K8 (COT)
Kinase Group
Ser⁄Thr Kinases: STE Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_005195
Molecular Weight
69.9 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 30-397
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
STE Unique Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4313
de9f86d903d15c3fba45a20e800f9d19_CmgtBuyProduct

COT/TPL2/MAP3K8 Monoclonal Antibody (clone 3H18L5), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
701352 100 µg 299.00

Description

This is a purified rabbit anti-human COT/TPL2/MAP3K8 monoclonal antibody that can be use in the validated applications of indirect ELISA and Western blot.

Antibody   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
3H18L5
Antibody Fragment
Whole Antibody
Target Gene
mitogen-activated protein kinase kinase kinase 8
Gene ID
1326
Gene Symbol
MAP3K8
Accession Number
P41279
Gene Aliases
COT, EST, ESTF, TPL2, MEKK8, Tpl-2, c-COT
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Product Size
100 µg
Protein Family
Kinases
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
701352
b159a64b1a92af8e3b6e6a2b7b86ab94_CmgtBuyProduct

COT/TPL2/MAP3K8 Oligoclonal Antibody (clone 3HCLC), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
710377 100 µg 285.00

Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes COT/ TPL2/ MAP3K8 in human samples.

Antibody Specifications:

• Validation in   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Flow Cytometry
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
3HCLC
Antibody Fragment
Whole Antibody
Target Gene
Mitogen-activated protein kinase kinase kinase 8
Gene ID
1326
Gene Symbol
MAP3K8
Accession Number
P41279
Gene Aliases
TPL2, Protoco oncogene c-Cot, ESTF, MAP3K8
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Product Size
100 µg
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Oncology
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
710377
dec8e258837aaed1e4bf025cf45b1678_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 3 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3176 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine MBP Thr-97 derived   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
BBRC vol. 61, pp 559-563 (1974), JBC, vol 252, p 4888 (1978)
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAPK1, MAPK3, MAPK12, MAPK13, MAP2K1, MAP2K2, MAP3K6, MAP2K8
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
Bovine MBP, Thr-97 derived peptide S5
Consensus seq Pro-X-(Ser⁄Thr)-Pro (APRTPGGRR)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3176
80cb8917b9a3c1ff43875579b27ff363_CmgtBuyProduct