PRKCA (PKC alpha) Recombinant Human Protein View 1 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2227 20 µg 560.00

Description

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
20 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Omnia® Bulk Substrate
Z'-LYTE™
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
P2227
75eb6b743ada36c969853f3b0af49856_CmgtBuyProduct

PRKCA (PKC alpha) Recombinant Human Protein View 2 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2232 5 µg 308.00

Description

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
5 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Omnia® Bulk Substrate
Z'-LYTE™
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
P2232
b85b374eec1e74eab5abadbc8d8fb3e0_CmgtBuyProduct

Staurosporine

Catalog # Unit Size List Price
PHZ1271 100 µg 170.00

Description

Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase.

Format/Formulation: Lyophilized   View full product details >

General Specifications

Form
Lyophilized
Gene ID
815, 816, 818, 91807
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
Product Size
100 µg
Purification
TLC
Inhibitor Type
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
466.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PHZ1271
bd5023e5e52651226561a9d54f1c6aba_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3180 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research
PV3180
b20b314506c47c1b0d85b1a3b0ebf4d2_CmgtBuyProduct

LanthaScreen® Tb-pSer (PKC) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3560 25 µg 3050.00

Description

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.

For use in combination with the   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3560
96f4f182d7a5de4d4709b2bda9f37451_CmgtBuyProduct

CellSensor® NFAT bla HEK 293T Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1538 1 vial 9880.00

Description

The CellSensor® NFAT-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor of Activated T Cells (NFAT) response element stably   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1538
2539a956de64106074c2b1dcb9f66c69_CmgtBuyProduct

CellSensor® NFAT-bla Jurkat Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1671 1 vial 9880.00

Description

The CellSensor® NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1671
181f301e4fe42dc18ae33f750d821191_CmgtBuyProduct

K252A

Catalog # Unit Size List Price
PHZ1131 100 µg 170.00

Description

K252a inhibits PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, the trk family of receptor tyrosine kinases, and numerous other kinases by acting as a competitive   View full product details >

General Specifications

Form
Lyophilized
Gene ID
5256, 5257, 5566, 5567, 5568, 5578, 5579, 5584, 5592, 816, 818, 91807
Sterility
Non-sterile
Product Size
100 µg
Inhibitor Type
Kinase Inhibitor (PKC Inhibitor)
Kinase Inhibitor
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor (PKA Inhibitor)
Kinase Inhibitor (Other)
Molecular Weight
467.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, trk family RTKs
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PHZ1131
83a314a9f5296cd54bcad4de96bcf568_CmgtBuyProduct

Fluorescein-PKC Substrate

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3506 1 mg 668.00

Description

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.

For use in combination with the LanthaScreen® Tb-pSer (PKC Substrate) antibody (PV3560) to   View full product details >

General Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3506
792a772cf71d6e51e988229ff9567823_CmgtBuyProduct

Omnia® S/T Peptide 8 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1081 1 kit 930.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1237 Da
Validated Kinases
MAP3K11 (MLK3), MAP3K9 (MLK1), MINK1, PRKD2 (Protein Kinase D2), PRKD1 (PKC mu), PKC
Amino Acid Sequence
Ac-(Sox)PGSFRRR-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
KNZ1081
33101b02879cf9102c7fe9aaacc7f399_CmgtBuyProduct