PRKCI (PKC iota) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3186 20 µg 560.00

Description

The PKC family of serine⁄threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5584
Species
Human
Target Gene
protein kinase C, iota
Gene Aliases
PRKCI (PKC iota)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
20 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002731
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3186
0cb1d0a55fed7985bf5e5810fc5da22d_CmgtBuyProduct

PRKCI (PKC iota) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3183 5 µg 308.00

Description

The PKC family of serine⁄threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5584
Species
Human
Target Gene
protein kinase C, iota
Gene Aliases
PRKCI (PKC iota)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
5 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002731
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3183
c01e14535cc632ce9aa13ffa777aec5d_CmgtBuyProduct

PKC-iota [pT555]/PKC Lambda [pT563] Polyclonal Antibody, Rabbit

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44968G 10 blots 299.00

Description

This rabbit anti-PKC-iota [pT555]/PKC Lambda [pT563] polyclonal antibody is specific to human and mouse PKC-iota [pT555]/PKC Lambda [pT563]. PKC-iota [pT555]/PKC Lambda [pT563]   View full product details >

General Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PKC Iota [pT555]/PKC Lambda [pT563]
Gene ID
5584
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Virology
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44968G
0e944254069510eb2831ea7b966348a2_CmgtBuyProduct

PKC iota/lambda, Rabbit pAb

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
400600Z 100 µg 299.00

Description

Rabbit anti-PKC-iota/lambda; Unconjugated Polyclonal antibody specific to Rat, Mouse, (Human) PKC-ι/λ. This antibody is validated for use in Western blotting. Anti-PKC-   View full product details >

General Specifications

Reactivity
Rat
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PKC iota
Gene ID
18759, 84006, 5584
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Virology
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
400600Z
469141fbdac017b312c2cd1a3f86c6d6_CmgtBuyProduct

K252A

Catalog # Unit Size List Price
PHZ1131 100 µg 170.00

Description

K252a inhibits PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, the trk family of receptor tyrosine kinases, and numerous other kinases by acting as a competitive   View full product details >

General Specifications

Form
Lyophilized
Gene ID
5256, 5257, 5566, 5567, 5568, 5578, 5579, 5584, 5592, 816, 818, 91807
Sterility
Non-sterile
Product Size
100 µg
Inhibitor Type
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor (Other)
Kinase Inhibitor (PKA Inhibitor)
Kinase Inhibitor
Kinase Inhibitor (PKC Inhibitor)
Molecular Weight
467.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, trk family RTKs
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PHZ1131
83a314a9f5296cd54bcad4de96bcf568_CmgtBuyProduct

Fluorescein-PKC Substrate

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3506 1 mg 668.00

Description

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.

For use in combination with the LanthaScreen® Tb-pSer (PKC Substrate) antibody (PV3560) to   View full product details >

General Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3506
792a772cf71d6e51e988229ff9567823_CmgtBuyProduct

LanthaScreen® Tb-pSer (PKC) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3560 25 µg 3050.00

Description

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.

For use in combination with the   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3560
96f4f182d7a5de4d4709b2bda9f37451_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3180 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research
PV3180
b20b314506c47c1b0d85b1a3b0ebf4d2_CmgtBuyProduct

PKC-iota [pT555]/PKC Lambda [pT563] Monoclonal Antibody (clone 31H34L29), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
700582 100 μg 299.00

Description

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes PRKC1 [pT555/pT563] in human and mouse.

ABfinity™ PKCiota[pT555]/PKClambda[pT563]   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
31H34L29
Antibody Fragment
Whole Antibody
Target Gene
PKC Iota [pT555]/PKC Lambda [pT563]
Gene ID
5584
Gene Symbol
PRKCI
Accession Number
P41743
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Frozen
Mass
100 µg
Neutralizing Antibody
No
Product Size
100 μg
Protein Family
Kinases & Inhibitors
Volume
200 µl
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
700582
19935f6540e9259ebef5ae344076e501_CmgtBuyProduct

Omnia® S/T Peptide 8 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1081 1 kit 930.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1237 Da
Validated Kinases
MAP3K11 (MLK3), MAP3K9 (MLK1), MINK1, PRKD2 (Protein Kinase D2), PRKD1 (PKC mu), PKC
Amino Acid Sequence
Ac-(Sox)PGSFRRR-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
KNZ1081
33101b02879cf9102c7fe9aaacc7f399_CmgtBuyProduct