Forensic News

Did You Know?

2013 marks the 60th anniversary of the discovery of DNA's structure and the 30th anniversary of the invention of PCR. Details on upcoming webinars and events, promotions, and more here.

60 years


Spotlight

The GlobalFiler™ STR Kit combines reduced amplification time with maximum data recovery power. Watch the video!

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Maximizing Data Quality

Article series focused on how to maximize data quality throughout the HID workflow.

  • Part I: The Importance of DNA Extraction in the Forensic DNA Workflow
  • Part II: DNA Quantitation
  • Part III: Maximizing Performance of Forensic STR Amplification Kits
  • Part IV: Maximizing the Performance of Capillary Electrophoresis Systems
  • Tech Note: Considerations for Evaluating Carryover on Applied Biosystems Capillary Electrophoresis Platforms in a HID Laboratory
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Life Technologies is proud to support DNA-PROKIDS, an international organization aimed at fighting human trafficking through the expanded use of DNA databases.

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Improvement of a non-FTA® Identifiler® Plus Direct-Amplification Methodology With Prep-n-Go™ Buffer

The modification of a direct-amplification method using the Bode Buccal DNA Collector™ device and the AmpFℓSTR® Identifiler® Plus PCR Amplification kit chemistry through the integration of Applied Biosystems® Prep-n-Go™ Buffer was evaluated and found to improve overall profile balance and allele peak height ratio. The results from several challenging samples which had previously exhibited severe peak height imbalances were significantly improved by using Prep-n-Go™ Buffer.

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Validation of Direct PCR on Bode Buccal DNA Collector™ Punches Using the Prep-n-Go™ Buffer and the AmpFℓSTR® NGM™ PCR Amplification Kit

One of the latest developments in forensic DNA typing—mainly for high-throughput genotyping of database samples—is the application of direct PCR without isolating DNA from the carrier matrix. Based on the results of the study, direct PCR amplification with the AmpFℓSTR® NGM™ kit of discs from Bode Buccal DNA Collector™ devices processed with Prep-n-Go™ Buffer is a rapid and easy-to-use method suitable for high-throughput CODIS-compatible typing of reference samples

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DNA Analysis of Ancient Bone and Tooth Samples by using PrepFiler® Express BTA Forensic DNA Extraction and AmpFℓSTR® NGM SElect™ PCR Amplification Kits

Analysis of ancient DNA (aDNA) from a biological sample constitutes a methodological challenge arising from its limited quantity, high level of degradation and increased likelihood of contamination. Our results demonstrate superior performance of the PrepFiler® Express BTA Extraction Kit as compared either to Wizard® Genomic DNA Purification Kit or QIAamp® DNA Micro Kit for processing ancient bone samples

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Maximizing the Power of Forensic DNA Databases With Next-Generation STR Technology

To date, forty-four countries have implemented nationwide criminal offender DNA database programs. However, a major persistent problem is that there are still many different loci sets throughout the world that are not interoperable, and when compared to each other a significant rate of adventitious matches may occur. To address these challenges, Life Technologies has developed an expanded global multiplex which, in its two, application-specific configurations will deliver unprecedented capabilities, not only in terms of discrimination, but also in terms of robustness, efficiency and overall ability to recover information from forensic samples within the current forensic laboratory environment.

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Using DNA to Fight Property Crime

DNA is a powerful law enforcement tool and is often referred to as the “fingerprint of the 21st century.” Today, the NYPD forensically investigates all applicable crime scenes (including homicides, sexual assaults, robberies, property crimes, gun possession, and auto theft) and submits recovered DNA evidence to the OCME's Biological Laboratory on a daily basis.

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