21346-EZ-Link-Amine-PEG2-230

Carboxyl groups can also be targeted for biotin labeling using amine-derivatized biotin molecules. They are found in the form of carboxy termini, and the side chain carboxyl groups in aspartate and glutamate residues. This reaction is mediated by a class of crosslinkers known as carbodiimides and results in the formation of an amide bond.

Choose the best carboxyl biotinylation reagent for your application

Product categories Product Product features Spacer arm (Å) Water  soluble? Cleavable? Membrane permeable?
Amine-PEG-Biotin Reagents Short, hydrophilic reagents for biotinylation of carboxyls via EDC 

20.4


22.9

Yes


Yes

No


No

No


No

Amine-PEG11-Biotin Long, hydrophilic reagent for biotinylation of carboxyls via EDC  53.2  Yes No  No 
Biocytin Useful for synthesizing long-chain biotinylation reagents  20.1 Yes No No
Pentylamine-Biotin Useful for EDC-mediated labeling and various assay strategies 18.9  Yes No  No 
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