A pyramidal neuron from rat hippocampus was first exposed to Alzheimer’s ß-amyloid peptide and then to the excitatory amino acid glutamate.
A pyramidal neuron from rat hippocampus was first exposed to Alzheimer’s ß-amyloid peptide and then to the excitatory amino acid glutamate. Confocal laser-scanning microscopy imaging using the intracellular Ca2+ indicator fluo-3 (Cat. no. F1241, F1242, F14218, F14242, F23915) shows that ß-amyloid peptide destabilizes the neuron’s calcium homeostasis and increases its vulnerability to excitotoxicity. The image was contributed by Mark P. Mattson, Sanders-Brown Center on Aging, University of Kentucky.
REF-52 fibroblasts. Cyclic AMP Fluorosensor (FlCRhR) and fura-2 AM Go ›
Pseudocolored images of changes in intracellular free Ca2+ in AtT-20/D16v-F2 cells, monitored at 9 sec intervals with fluo-4, AM (F14201, F14202, F14217, F23917). Go ›
Dual-emission ratiometric measurement of lysosomal pH using LysoSensor™ Yellow/Blue dextran. Go ›
Phagocytosis in MMM Cells using pHrodo™ Red E. coli BioParticles® Conjugate® (Catalog # P35361) Go ›
Human peripheral blood leukocytes stained with CD45 FITC and antibody clone 581 PerCP-Cy®5.5 conjugate (top, Cat. No. A14949) or mouse IgG1,kappa PerCP-Cy®5.5 isotype control (bottom). Cy®togram gated for total live CD14 negative lymphocyte population. Go ›
Human peripheral blood leukocytes stained with CD34 antibody (clone 581) Pacific Blue conjugate (top, Cat. No. A14947) or mouse IgG1,kappa Pacific Blue isotype control (bottom) and costained with CD45 FITC, CD14 PE, and 7-AAD, then analyzed via gating on total live and CD14-negative lymphocyte population. Go ›
Developing Drosophila embryo Go ›
Cytoskeleton of a mixed population of granule neurons and glial cells Go ›